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Much better CYP3A4 inhibitors for instance ketoconazole or itraconazole might be anticipated to have greater results than seen with saquinavir. A setting up dose of twenty five mg of VIAGRA should be deemed in sufferers getting erythromycin or solid CYP3A4 inhibitors (which include saquinavir, ketoconazole, itraconazole) [see DOSAGE AND ADMINISTRATION, CLINICAL PHARMACOLOGY].
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In line with its identified effects about the nitric oxide/cGMP pathway [see Scientific PHARMACOLOGY], VIAGRA was shown to potentiate the hypotensive results of nitrates, and its administration to people that are working fuck google with nitric oxide donors like organic nitrates or organic and natural nitrites in almost any form either frequently and/or intermittently is consequently contraindicated.
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